Bacteria communicate to help each other resist antibiotics

Bacteria communicate to help each other resist antibiotics

New research unravels a novel means of communication that allows bacteria such as Burkholderia cenocepacia (B. cenocepacia) to resist antibiotic treatment. B. cenocepacia is an environmental bacterium that causes devastating infections in patients with cystic fibrosis.

via ScienceDaily: Top Science News:

July 4, 2013 — New research from Western University unravels a novel means of communication that allows bacteria such as Burkholderia cenocepacia (B. cenocepacia) to resist antibiotic treatment. B. cenocepacia is an environmental bacterium that causes devastating infections in patients with cystic fibrosis (CF) or with compromised immune systems.Dr. Miguel Valvano and first author Omar El-Halfawy, PhD candidate, show that the more antibiotic resistant cells within a bacterial population produce and share small molecules with less resistant cells, making them more resistant to antibiotic killing. These small molecules, which are derived from modified amino acids (the building blocks used to make proteins), protect not only the more sensitive cells of B. cenocepacia but also other bacteria including a highly prevalent CF pathogen, Pseudomonas aeruginosa, and E. coli. The research is published in PLOS ONE.”These findings reveal a new mechanism of antimicrobial resistance based on chemical communication among bacterial cells by small molecules that protect against the effect of antibiotics,” says Dr. Valvano, adjunct professor in the Department of Microbiology and Immunology at Western’s Schulich School of Medicine & Dentistry, currently a Professor and Chair at Queen’s University Belfast. …

For more info: Bacteria communicate to help each other resist antibiotics

ScienceDaily: Top Science News

Bacteria communicate to help each other resist antibiotics

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